Effect of mAb to VCAM-1 and MAdCAM-1 on MCp recruitment to the inflamed lung. (A) Number of lung MNCs recovered per mouse from sensitized C57BL/6 mice not challenged with aerosolized OVA (No Challenge) or that had received injections of HBSS or the indicated mAb and then challenged with aerosolized OVA. Values are the mean ± SEM from 3 experiments with 4 determinations in each group. (B) Concentration of MCp's (MCp's/10⁶ MNCs) in the lungs of the same mice. (C) Total number of MCp's per lung in the same mice. ^*P < .05, ^**P < .01, as determined by the 2-tailed Student t test.