Figure 1.
Triptolide induced significant cell growth arrest and cell death in leukemic cells. Cells at a density of 0.2 × 106/mL were treated with various concentrations of triptolide. (A) Structure of triptolide. (B) Viable leukemic cells treated with triptolide, as determined by trypan blue exclusion after 24 and 48 hours. (C) Cell death induced by triptolide in various leukemic cells, as determined by annexin V staining with PI after 24 or 48 hours of treatment.
