Variation in FcγRIIa/FcγRIIb2 mRNA ratios within healthy volunteers. (A) Neutrophils from 60 healthy volunteers were isolated, and FcγRIIa/FcγRIIb2 mRNA ratios were determined. Four nonoverlapping groups were observed. There was an equal distribution of males and females over the groups without bias of age toward the groups. There was a high prevalence of FcγRIIa/FcγRIIb2 mRNA ratios 1:1 (n = 23; 38%) and 2:1 (n = 17; 28%), whereas 3:1 (n = 6; 10%) and 4:1 (n = 14; 24%) were less frequently observed. (B) FcγRIIa/FcγRIIb2 mRNA ratios plotted against age. No correlation between age and FcγRIIa/FcγRIIb2 mRNA ratios was found (r² = 0.006 987 and P = .564).