The influence of the absence of the BKB2R receptor on the time to thrombosis in the Rose Bengal model of carotid artery occlusion. Control mice (B6129SF2/J mice, CN, n = 19) and BKB2R^-/- mice (n = 9) were examined for their time to carotid artery occlusion (see “Materials and methods”). Additionally, control mice were treated with increasing concentrations of icatibant (HOE140) (0.91 mg/kg to 9.13 mg/kg, given intraperitoneally) and the time to thrombosis was determined. These latter data are the mean plus or minus SD of 4 or more experiments at each experimental concentration of HOE140.