Clotting factor level in relation to carrier status shown for participants for whom clotting factor level is known. This box-whisker plot shows the median and the interquartile range of clotting factor activity levels in carriers and noncarriers. The box is marked by the first and the third quartile; the whiskers indicate the range. The stacked asterisks indicate two extremes (2.09 and 2.19 IU/mL).