Induction of T-cell killing of EBV-immortalized LCL cells. A mixed lymphocyte reaction was performed by incubating T cells with their targets (LCL cells) in the presence (+) or absence (-) of the anti-CD95–neutralizing mAb BD29 or anti-CD95 ligand–neutralizing mAb BR17. Anti-CD95 BD29 mAb and anti-CD95 ligand BR17 mAb were preincubated for 15 minutes at room temperature with LCL cells or purified primed T cells, respectively, before coincubation of T cells with their targets. Control indicates LCL cells incubated with an irrelevant anti-NGFR antibody; LCL + primed T cells, LCL cells incubated with T cells primed against their target by coculture with the same LCL cells irradiated at 75 Gy for 5 days.