G₂M cell-cycle block induced by survivin down-regulation in KBM5 and KBM5-STI571 cells. KBM5 and KBM5-STI571 cells were treated with Sur-AS-ODN and its control oligonucleotide Sur-NS-ODN. Cell-cycle distribution was analyzed at 48 hours after PI staining. Sol cont indicates solution T control; prog cont, nucleofection program K17 control; NS, Sur-NS-ODN control; AS, Sur-AS-ODN.