BCL6 mRNA increases after chemotherapy/radiotherapy in human patients. BCL6 (A) and p21 (B) mRNA levels in WBCs taken from patients treated with chemotherapy/radiotherapy were determined using QPCR and normalized to β₂-microglobulin. Results display mean ± SD of quantifications repeated 3 times, each in triplicate. Labels adjacent to the x-axis indicate the time in which the PB was taken. Fold ratios of mRNA levels were calculated in comparison to the control samples for each patient. Ctr indicates control; d, number of days of the detailed treatment; CP, cyclophosphamide; IR, whole body irradiation; patient A, a 23-year-old female with prolymphocytic leukemia; patient B, a 29-year-old male with T-ALL; patient C, a 39-year-old female with Philadelphia-positive ALL. □ indicates control.