Validations of predictions of thrombosis. (A) Expression profiles of genes that classify and predict thrombosis. Image depicts a group of 50 genes selected to differentiate patients with APS (aPLA + VTE) from patients with asymptomatic aPLAs in the training (n = 54) and validation (n = 35) sets. (B) Leave-one-out cross-validation (CV) analysis in the training cohort (n = 54) of APS patients (red) and asymptomatic patients with aPLAs (blue). Details are the same as described in Figure 2. (C) Validation of the binary regression model in a blinded independent cohort of 35 subjects (21 patients with APS [red] and VTE, 14 patients with asymptomatic aPLAs [blue]). Details are the same as in Figure 2.