Figure 3.
Figure 3. IRp60 inhibits eosinophil-mediated fibroblast proliferation. Eosinophils previously incubated with either anti-IRp60 or control antibodies (isotype, anti-p58.2) followed by the cross-linker sheep anti-mouse F(ab′)2 were washed and incubated with various concentrations of IL-5/GM-CSF (50 ng/mL) for 18 to 20 hours. Cell supernatants were assessed for their ability to induce 3T3 fibroblast proliferation as assessed by [3H]-thymidine incorporation. Data are expressed as mean CPM/well ± SD (n = 3; **P < .005).

IRp60 inhibits eosinophil-mediated fibroblast proliferation. Eosinophils previously incubated with either anti-IRp60 or control antibodies (isotype, anti-p58.2) followed by the cross-linker sheep anti-mouse F(ab′)2 were washed and incubated with various concentrations of IL-5/GM-CSF (50 ng/mL) for 18 to 20 hours. Cell supernatants were assessed for their ability to induce 3T3 fibroblast proliferation as assessed by [3H]-thymidine incorporation. Data are expressed as mean CPM/well ± SD (n = 3; **P < .005).

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