Cerebral microvessels perfused with FITC-dextran. The plasma-demarcated capillary networks show a broad array of twists, turns, and junctions in the striatum from a control mouse (A). Irregularly dilated cerebral microvessels with leakage of FITC-dextran was detected in the striatum of an SS mouse (B, C). Panel C is a high magnification of boxed area in panel B (Bar = 40 μm).