p53 induces expression of BCL6. BCL6 represses the transcription of p53, allowing continuous cell survival and proliferation in the face of DNA damage, and these changes may lead to lymphoma. Illustration by A. Y. Chen.

p53 induces expression of BCL6. BCL6 represses the transcription of p53, allowing continuous cell survival and proliferation in the face of DNA damage, and these changes may lead to lymphoma. Illustration by A. Y. Chen.

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