Therapeutic efficacy of 2L-Rap-hLL1-γ4P in SCID mice bearing Raji cells. SCID mice (7 to 8 per group) were inoculated intravenously with 2.5 × 10⁶ Raji cells. Mice were treated with a single intravenous bolus dose of 50 μg 2L-Rap-hLL1-γ4P at 1 day (▪), 5 days (•), or 10 days (▴) after inoculation of cells. Control animals received saline (□), 50 μg naked hLL1 (▵), 7 μg rRap (⋄), a mixture of naked hLL1 and rRap (○), or nonspecific immunotoxin Rap-hRS7 (^*) at 1 day after inoculation of Raji cells.