IFN-γ and IL-10 produced by sets of T-cell clones that are representative of results in 81 haploidentical transplant donors, 46 control transplant recipients, and 35 transplant recipients who received adoptive therapy. (A) Aspergillus specific. (B) CMV specific. Donor clones (○) displayed protective high IFN-γ and very low IL-10 patterns. Spontaneously recovering clones in control haploidentical recipients (▪) displayed nonprotective lower IFN-γ and higher IL-10. After adoptive therapy, clones (•) displayed protective high IFN-γ and very low IL-10, overlapping with the pattern observed in their healthy donors (P < .001 vs noninfused patients; P = ns vs donors).