Posttransplantation CD4⁺ and CD8⁺ T-cell counts in 35 transplant patients who received T-cell therapy and in 46 control transplant recipients. X axes: weeks after transplantation and number of evaluable patients at each time point. (A) CD4⁺ cells in immunotherapy (straight line) and control cohorts (broken line). (B) CD8⁺ cells in immunotherapy (straight line) and control cohorts (broken line). Compared with controls, CD4⁺ and CD8⁺ cell counts were higher in immunotherapy-treated patients, reaching significance at 12 weeks (P < .01 and P < .02, respectively) and 24 weeks (P < .05 for both). A significant difference persisted in CD8⁺ counts at 36 weeks (P < .02 vs controls).