Up-regulation of β1-integrin and FN in the ROP model. (A) Typical fluorescence staining patterns for β1-integrin (i; green) and FN (ii; red) and the overlay picture (iii) and appropriate negative control (first antibody omitted) (iv) of retinas from control mice (top row) or mice subjected to the ROP model (bottom row) are shown. (B) Typical fluorescence staining patterns for β1-integrin (i; green) and PECAM-1 (ii; red) and the overlay picture (iii) and appropriate negative control (first antibody omitted) (iv) of retinas from control mice (top row) or mice subjected to the ROP model (bottom row) are shown. (C) Typical fluorescence staining patterns for PECAM-1 (i; green) and FN (ii; red) and the overlay picture (iii) and appropriate negative control (first antibody omitted) (iv) of retinas from control mice (top row) or mice that were subjected to the ROP model (bottom row) are shown. INL indicates inner nuclear layer; ONL, outer nuclear layer.