Proliferative activity induced by autologous DCs on normal NK cells, CD3^- GL, and CD3⁺ GL from patients with LDGL. (A) Autologous DCs (n = 6) were able to induce significant proliferation in normal NK cells, whereas no proliferative activity was induced in T lymphocytes (not shown). (B) Proliferative activity induced by DCs in patients with CD3^- LDGL (n = 6) was consistent with healthy control subjects (ratio DC/NK cells, 1:1). Immature DCs were able to induce a higher proliferation of CD3^- GLs as compared with mature DCs. The addition of IL-15 showed a slight additive effect on proliferation. (C) No proliferative effect was induced by autologous DCs in CD3⁺ GLs (n = 5). Data represent mean ± SEM. ^*P < .05; ^**P < .1.