Figure 6.
NrasG12D cooperating mutation overcomes heritable resistance to AML initiation. (A-B) Kaplan-Meier survival curves after E10.5 or P0 ME induction using Tet-On-ME and Tet-On-ME/NrasG12D models. (C) Survival curves of recipient mice after transplantation of P0 or P28 LSK after ME induction at E10.5 or P21, respectively. P values are indicated and were calculated by the log-rank test.

NrasG12D cooperating mutation overcomes heritable resistance to AML initiation. (A-B) Kaplan-Meier survival curves after E10.5 or P0 ME induction using Tet-On-ME and Tet-On-ME/NrasG12D models. (C) Survival curves of recipient mice after transplantation of P0 or P28 LSK after ME induction at E10.5 or P21, respectively. P values are indicated and were calculated by the log-rank test.

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