Figure 4.
Oncoplot illustrating HR features at an individual patient level (n = 135), including IMS/IMWG-defined HRCAs, GEP-HR, t(11;14), and elevated b2m or LDH. ER as in PFS (defined as <18 months or <24 months) and OS events (at 48 and 60 months) are shown in red, while no event displayed in gray. Co-occurrence of ≥2 HR features appear in dark blue, single HR features in light purple, and no HR feature in white. Translocation t(11;14) is separately listed in green. Elevated laboratory parameters (b2m, LDH) are marked in dark purple. TP53 mutation status was not included in this analysis, as only 11 patients in the study had available information. LDH, lactate dehydrogenase. Figure created with biorender.com. Houlston R. (2025) https://biorender.com/0vv82j9.

Oncoplot illustrating HR features at an individual patient level (n = 135), including IMS/IMWG-defined HRCAs, GEP-HR, t(11;14), and elevated b2m or LDH. ER as in PFS (defined as <18 months or <24 months) and OS events (at 48 and 60 months) are shown in red, while no event displayed in gray. Co-occurrence of ≥2 HR features appear in dark blue, single HR features in light purple, and no HR feature in white. Translocation t(11;14) is separately listed in green. Elevated laboratory parameters (b2m, LDH) are marked in dark purple. TP53 mutation status was not included in this analysis, as only 11 patients in the study had available information. LDH, lactate dehydrogenase. Figure created with biorender.com. Houlston R. (2025) https://biorender.com/0vv82j9.

This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal