Figure 4.
Explorative untargeted metabolomics. (A) PCA of HX and HCs, divided per subgroup of PIEZO1-HX (n = 10) and KCNN4-HX (n = 3) displayed with 95% confidence interval. (B) Heat map demonstrating the top 50 most distinctive metabolites among the HCs and patients with PIEZO1-HX and KCNN4-HX. PC, principal component.

Explorative untargeted metabolomics. (A) PCA of HX and HCs, divided per subgroup of PIEZO1-HX (n = 10) and KCNN4-HX (n = 3) displayed with 95% confidence interval. (B) Heat map demonstrating the top 50 most distinctive metabolites among the HCs and patients with PIEZO1-HX and KCNN4-HX. PC, principal component.

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