Timing and severity of clinically relevant infections by location and etiology. (A) 0.4 mg/kg weekly cohort. (B) 0.8 mg/kg EOW cohort. (C) Prior TCR cohort. The y-axis (days) was the relative start date of the AE. Patients with multiple infections are represented as separate points on the plot. Patients included once on the plot are represented as circles, whereas patients included more than once are represented as triangles. Two patients were excluded from the location figures: 1 had a central nervous system event in the EOW cohort, and 1 had a dental event in the prior TCR cohort.