CRP-mediated signaling is enhanced in Syk(Y317F) platelets. (A) Representative western blots showing the phosphorylated and total proteins, as indicated, in platelets from Syk(Y317F) and WT littermate mice stimulated with the indicated concentrations of CRP for 3 minutes. (B-E) Quantification of the indicated phosphorylated residues, depicted as the ratio of pY to total protein. pPLCγ, phosphorylated PLCγ.