Progressively worse UACR and eGFR categories were associated with CKD progression and survival. CKD progression, defined by a 40% decline in eGFR or development of ESKD, was associated with (A) worsening UACR and (B) eGFR categories based on 2 consecutive measures ≥3 months apart. Overall survival was also associated with (C) worsening UACR and (D) eGFR categories (log-rank P values are provided).