Baseline risk factors and response outcomes. (A) Oncoprint heat map depicting per patient baseline characteristics that may affect outcome, panel of baseline comutations, IPSS-R category, cytogenetics, and cytogenetic risk classification presented by best overall response. (B) Box and whisker plot of number of comutated genes by best overall response. Due to the small patient numbers, there was insufficient power to demonstrate a statistical difference between response categories. P > .05, for all comparisons including CR vs non-CR (ordinary 1-way analysis of variance) and responders vs nonresponders (unpaired t test). (C) IDH1 mutation type, based on local laboratory results. BOR, best overall response.