Treatment outcomes and response. (A) Consort diagram. (B) Treatment duration and follow-up (F/U) postcompletion according to disease and RT dose level. Durvalumab treatment indicated by colored solid bars. Triangles represent best response, circle represents PD. Black arrows illustrate participants who were alive at data lock. Participants in the PET substudy are denoted by colored arrows according to tracer. (C) TMTV change in lesions according to RT dose level and in-treated volume vs out-of-treated volume responses. X represents participants who did not have a F/U PET/CT. CNS, central nervous system; MRI, magnetic resonance imaging; CMR, complete metabolic response; PMR, partial metabolic response; SD, stable disease; PD, progressive disease.