Figure 3.
Marrow lymphocytes demonstrate unique phenotypic features. (A) Heat map of CD69 and CD25 expression in the marrow and blood stratified by lymphocyte subset tracked longitudinally. Color denotes the percentage of the population expressing CD69 and CD25, respectively, of the total cell population. Wilcoxon signed-rank test of expression in the marrow vs blood is included in supplemental Table 9. (B) Kinetics of CD4 T-cell and CD8 T-cell reconstitution by graft source. Shown are CD4 and CD8 frequencies out of the sum of CD4 and CD8 T-cell populations; 1-sample Mann-Whitney test of CD4/(CD4 + CD8) against the neutral null of 0.5 (supplemental Table 10). pre-tx, pretransplant.