Factors influencing the post-DDAVP pharmacokinetic parameters of the FVIII. (A) Influence of F8 genotype, body weight, and ABO blood type (O and non-O). (B) Influence of the different F8 variant types. F8 variants were divided in 2 groups: null variants predicted to be associated with no FVIII synthesis, and non-null variants with a less deleterious effect on FVIII synthesis.
Figure 5.

Factors influencing the post-DDAVP pharmacokinetic parameters of the FVIII. (A) Influence of F8 genotype, body weight, and ABO blood type (O and non-O). (B) Influence of the different F8 variant types. F8 variants were divided in 2 groups: null variants predicted to be associated with no FVIII synthesis, and non-null variants with a less deleterious effect on FVIII synthesis.

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