TasQ eliminates B-CLL cells in a PDX model. (A) Clinical information of patient samples from the 2 donors used in this experiment. (B) Schematic representation of the experiment design. (C-D) Representative spleen pictures and FC dot plots after 3 weeks of treatment. (E-F) Spleen weight and absolute count of splenic B cells at week 3 after treatment. ∗∗∗∗P < .0001; ∗∗∗P < .001 (paired t test). FISH, fluorescence in situ hybridization; hCD19, human CD19; mCD45, mouse CD45; WBC, white blood cells. Uriepero-Palma, A. (2025) https://BioRender.com/04mb8cm. Panel B created with BioRender.com.
Figure 6.

TasQ eliminates B-CLL cells in a PDX model. (A) Clinical information of patient samples from the 2 donors used in this experiment. (B) Schematic representation of the experiment design. (C-D) Representative spleen pictures and FC dot plots after 3 weeks of treatment. (E-F) Spleen weight and absolute count of splenic B cells at week 3 after treatment. ∗∗∗∗P < .0001; ∗∗∗P < .001 (paired t test). FISH, fluorescence in situ hybridization; hCD19, human CD19; mCD45, mouse CD45; WBC, white blood cells. Uriepero-Palma, A. (2025) https://BioRender.com/04mb8cm. Panel B created with BioRender.com.

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