Somatic, nonsynonymous SNVs in cancer driver genes in Vk∗MYC:Wwox KO PBTs. Oncoplot displaying nonsynonymous SNVs in cancer driver genes identified through exome sequencing of CD138+ BM PCs and Vk∗MYC:Wwox KO PBTs. Each column represents an individual mouse, grouped as indicated at the top of the plot, and each row corresponds to mutations detected in a specific gene for these mice. In the Vk∗MYC:Wwox KO-PBT group, the first 3 columns represent PBPs, whereas the last column represents a PBL. Blue squares indicate the presence of mutations in the corresponding gene for each sample.
Figure 5.

Somatic, nonsynonymous SNVs in cancer driver genes in Vk∗MYC:Wwox KO PBTs. Oncoplot displaying nonsynonymous SNVs in cancer driver genes identified through exome sequencing of CD138+ BM PCs and Vk∗MYC:Wwox KO PBTs. Each column represents an individual mouse, grouped as indicated at the top of the plot, and each row corresponds to mutations detected in a specific gene for these mice. In the Vk∗MYC:Wwox KO-PBT group, the first 3 columns represent PBPs, whereas the last column represents a PBL. Blue squares indicate the presence of mutations in the corresponding gene for each sample.

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