Patient-reported symptoms of illness during the study interval. Seven of the 26 patients reported at least 1 subjective symptom of possible illness during the study interval, accounting for 45 of the 1434 diary days (3.1%) recorded (A). Forty of those 45 days (88%) were after transfusion with PS-PE high units (4.0% of diary days; 103 involved transfused units; P = .004), and no symptoms were noted in those who received PS-PE–low units (0% of diary days and 27 involved transfused units). The odds of having subjective symptoms reported during the physical examination after transfusion with PS-PE–high units was 1.94 (95% CI, 1.06-3.54). No statistically significant differences were observed when comparing study arms (P =.1; odds ratio, 1.41; 95% CI, 0.25-7.87). (B) The most common symptoms noted were upper respiratory in nature (ie, rhinitis, cough, and fatigue).
Figure 5.

Patient-reported symptoms of illness during the study interval. Seven of the 26 patients reported at least 1 subjective symptom of possible illness during the study interval, accounting for 45 of the 1434 diary days (3.1%) recorded (A). Forty of those 45 days (88%) were after transfusion with PS-PE high units (4.0% of diary days; 103 involved transfused units; P = .004), and no symptoms were noted in those who received PS-PE–low units (0% of diary days and 27 involved transfused units). The odds of having subjective symptoms reported during the physical examination after transfusion with PS-PE–high units was 1.94 (95% CI, 1.06-3.54). No statistically significant differences were observed when comparing study arms (P =.1; odds ratio, 1.41; 95% CI, 0.25-7.87). (B) The most common symptoms noted were upper respiratory in nature (ie, rhinitis, cough, and fatigue).

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