Figure 3.
Clinical trial simulation of the percentage of individuals with either OS at 24 months or CIR at 12 months. Simulated percentage of individuals (of a study sample size of 18) with OS at 24 months (A) and CIR at 12 months (B) using 4 different FLU dosing regimens. R1, 25 mg/m2 per day for 3 days; R2, 30 mg/m2 per day for 4 days; R3, age-adjusted dosing; or R4, TDM-guided dosing. Horizontal line, median; box, 25th to 75th percentile; whiskers, quartile range.