CLL cells were internalized by BMF and displayed active within-BMF movements. Time-lapsed microscopy showing the live dynamic process of CIC. Time-lapse live cell imaging was acquired on Leica SP8 TCS laser scanning confocal microscope equipped with an incubator for temperature, humidity and CO₂ control. Two fields were captured with z-stack of 0.5 μm/slice and a total of 10 slices at original magnification ×20 magnification and 2 minutes interval for 17 hours. Two movies are included. Suggestion is to play movies slowly: click play then pause, then click along the progression bar, and follow 1 cell at a time through different movie frames.