Major findings of Cappenberg et al on the role of Myo9b in neutrophils. Major findings of Cappenberg et al on the role of Myo9b in neutrophil migration (A) and effector functions (B) as well as the mechanism underlying its regulatory role involving integrin β2 (C). Studies were carried out on Myo9b KO–/– and wild-type+/+ mice. ↑, increased; ↓, decreased; dashed line, partial impact. CXCL1, chemokine (C-X-C motif) ligand 1; Rap-1, Ras-related protein 1.

Major findings of Cappenberg et al on the role of Myo9b in neutrophils. Major findings of Cappenberg et al on the role of Myo9b in neutrophil migration (A) and effector functions (B) as well as the mechanism underlying its regulatory role involving integrin β2 (C). Studies were carried out on Myo9b KO–/– and wild-type+/+ mice. ↑, increased; ↓, decreased; dashed line, partial impact. CXCL1, chemokine (C-X-C motif) ligand 1; Rap-1, Ras-related protein 1.

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