Figure 3.
Baseline LILRB4 expression and correlation with clinical efficacy in patients with HMA-naïve CMML in part 2B. (A) Baseline LILRB4 expression on leukemic blasts by flow cytometry in individual patient BM samples. The percentages of LILRB4-positive blasts (LILRB4+ blast%) among BM blasts (left); and LILRB4 copy number per blast in BM (right). The bars indicate mean and standard deviations. (B) Correlation of baseline LILRB4 expression on BM blasts with clinical efficacy in patients with HMA-naïve CMML. Vertical dotted line represented 4500 copies of LILRB4 per cell and horizontal dotted line represented 50% LILRB4-positive blasts. Asterisk (∗) indicates 1 patient not shown due to hemodiluted BM sample.