The prognostic role of FL location. (A) Simultaneous PET and DWI scans for a patient newly diagnosed with MM are shown. Examples of FLs in the pelvis, rib, and femur are indicated by blue, orange, and red arrows, respectively. (B) PFS for patients with FLs in the long bones (femur or humerus) detected by DWI or PET at baseline, compared with all other patients. (C) Stratification of the other patients into those without FLs, those with FLs in the pelvis or spine only, and those with FLs in the ribs or shoulders. Group comparisons were performed using the log-rank test.