Figure 3.
JMML stem cells express a broad repertoire of NK cell ligands similar to that of AML cells. Immature JMML and AML CD34+ populations (n = 3 JMML samples and n = 1 AML sample) were examined for surface expression of ligands for various NK cell–activating and –inhibitory receptors by mass cytometry. Results are plotted as normalized expression of median metal intensity (MMI) (A) or percent positive cells (B). PDL1, Programmed Death-Ligand 1.