PFS and OS stratified by frailty. Kaplan-Meier curves were used to show the probability of survival without disease progression or death (A) as well as survival without death alone (B) based on frailty status. Both curves did not show statistically significant difference in median survival probability when HR calculations were performed: median PFS was NR (range, 12 to NR) in the frail group and 11 months (range, 5 to NR) in the nonfrail group (P = .051); median OS was 37 months (range, NR to NR) in the frail group and 25 months (range, 16 to NR) in the nonfrail group (P = .37). F, frail; NF, nonfrail.