Differential functional status and repertoire diversity of T cells between the 2 groups. (A) The DEGs were visualized by the volcano plots. (B-C) The bar plots showed the GO_BP pathways enriched by the DEGs of CD4⁺ Th cells in the HA (B) and HB (C) groups. (D) Numbers of unique T-cell clonotypes in the HA and HB groups. (E) Top clonal proportions of T-cell clonotypes with specific indices of each sample. (F) Rare clonal proportions of T-cell clonotypes with specific counts of each sample. (G) The projection of top 10 clonotypes and others in all 10 samples on the UMAP of T and NK cells.