Further clustering of T- and NK-cell subsets and their general features. (A) UMAP was used for the dimension reduction of visualization of T and NK subsets. (B) The expression levels of the markers for the annotation of T and NK subsets were shown by the dot plot. (C) The ratios of each T and NK subsets in each sample. The legend in panel A also applies to panel C. (D-K) Student t test was used to analyze the difference of T-cell subsets, including dual negative (DN) T cell (D), naïve CD4⁺ T cell (E), CD4⁺ Th cell (F), regulatory T (Treg) cell (G), naïve CD8⁺ T cell (H), CD8⁺ CTL (I), exhausted T cell (J), and γδ T cell (K) in total T cells between the 2 groups.