OS and LFS of patients with MDS within different risk groups. (A) OS for patients in low- and high-risk IPSS-R groups. (B) LFS for patients in low- and high-risk IPSS-R groups. (C) OS for patients in low- and high-risk IPSS-M groups. (D) LFS for patients in low- and high-risk IPSS-M groups. (E) OS for patients with <3 mutations compared with those with ≥3 mutations. (F) LFS for patients with <3 mutations compared with those with ≥3 mutations.