Total number of clonal IG/TR rearrangements per patient for pediatric and adult patients with ALL. The x-axis represents the number of clonal rearrangements per patient, whereas the y-axis shows the patient count. Pediatric patients are displayed on the left and adult patients on the right. Different colors indicate immunophenotypes as defined by European Group for the Immunological Classification of Leukemia (EGIL). The difference in the number of markers per patient between children and adults is highly significant (P = 2.5e-38). Avg, average.