PFS and OS by risk category using the PET-based score compared to FLIPI-2 in the Mayo/Iowa SPORE MER cohort. (A) PFS using the PET-based score. The KM Ests are shown with 2-year PFS of 49% in the high-risk group (score, 4-6), 69% in the intermediate-risk group (score, 2-3), and 79% in the low-risk group (score, 0-1). (B) PFS using FLIPI-2. The KM Ests are shown with 2-year PFS of 59% in the high-risk group (score, 3-5), 75% in the intermediate-risk group (score, 1-2), and 87% in the low-risk group (score, 0). (C) OS using the PET-based score. The KM Ests are shown with 2-year OS of 80% in the high-risk group, 91% in the intermediate-risk group, and 97% in the low-risk group. (D) OS using FLIPI-2. The KM Ests are shown with 2-year OS of 85% in the high-risk group, 95% in the intermediate-risk group, and 99% in the low-risk group. CI, confidence interval; NE, not estimable.