Figure 2.
Proteomic landscape of AML. (A) PC analysis plot displaying inflammatory cytokines in both patients with AML and HDs. Each dot represents 1 patient. (B) Volcano plot showing differentially expressed proteins between patients with AML and HDs. P values were calculated using “limma” package in R. (C) Network heat map showing the coexpression of targets in each identified module coded by module color. (D) Kaplan-Meier curves of high and low module 1 and 4 signature scores in the in-house cohort. (E) Protein interaction networks for modules 1 and 4. FC, fold change; ME, module eigengene; Padj, adjusted P value; PC2, principal component 2.

Proteomic landscape of AML. (A) PC analysis plot displaying inflammatory cytokines in both patients with AML and HDs. Each dot represents 1 patient. (B) Volcano plot showing differentially expressed proteins between patients with AML and HDs. P values were calculated using “limma” package in R. (C) Network heat map showing the coexpression of targets in each identified module coded by module color. (D) Kaplan-Meier curves of high and low module 1 and 4 signature scores in the in-house cohort. (E) Protein interaction networks for modules 1 and 4. FC, fold change; ME, module eigengene; Padj, adjusted P value; PC2, principal component 2.

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