Immune cell profiling of patch-, plaque-, and tumor-stage MF. UMAP (A) and correlation plot (B) revealed that the immune cell composition of tumor-stage MF was distinct from patch- or plaque-stage MF. (C) Pairwise box plots of immune cell scores (memory B cells, plasma cells, follicular helper T cells, activated NK cells, M0 macrophages, M2 macrophages, activated dendritic cells, resting mast cells, and activated mast cells) determined by CIBERSORTx in 32 immune cell areas. (D) Pairwise box plots of immune cell scores (memory B cells, plasma cells, eosinophils, activated NK cells, M1 macrophages, M2 macrophages, monocytes, resting mast cells, and activated mast cells) analyzed with CIBERSORTx in lymphoma cell areas.