Figure 3.
Axi-cel response rates by V2Vt. Response rate (A), adjusted ORs of ORR and CR (B), and adjusted DOR (C) by V2Vt in patients treated with axi-cel. Patients were from the CIBMTR registry PASS Cohort. Covariates for stepwise selection and multivariable adjustment were age, sex, race, ethnicity, ECOG PS before infusion, comorbidities (pulmonary, cardiac/cerebrovascular/heart valve disease, hepatic, and renal), histologic transformation, disease characteristics at initial diagnosis (double/triple hit, disease stage, elevated LDH, and >1 extranodal involvement), chemosensitivity before infusion, number of lines of prior therapy, prior HCT, year of infusion, time from initial diagnosis to infusion, and use of bridging therapy. PR, partial response.