Figure 2.
In vitro validation of a human/NHP cross-reactive CD33-directed CAR construct. (A) Representative schematic of CAR33 design with bicistronic tCD19 reporter. (B) CRA results of human CAR33 T cells cultured with CD33+ or CD33− ML-1 cells. (C) xCELLigence killing assay of macaque CAR33 T cells cultured with CD33+/− LLCMK2 cells. IgG4, immunoglobulin G4.

In vitro validation of a human/NHP cross-reactive CD33-directed CAR construct. (A) Representative schematic of CAR33 design with bicistronic tCD19 reporter. (B) CRA results of human CAR33 T cells cultured with CD33+ or CD33− ML-1 cells. (C) xCELLigence killing assay of macaque CAR33 T cells cultured with CD33+/− LLCMK2 cells. IgG4, immunoglobulin G4.

This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal