Sankey plot of responses by independent central review at weeks 5, 12, and 36. Deeper responses were observed at week 12, with 8 of 14 patients with PR at week 5 achieving CR, and 3 of 14 maintaining PR; 4 of 18 patients with SD at week 5 achieving CR and 6 of 18 achieving PR. Additionally, 2 patients with PR at week 12 achieved CR at week 36.