Impact of pre–allo-SCT remission status on clinical outcomes. Kaplan-Meier curves of (A) OS and (B) LFS. Cumulative incidences (CIs) of (C) NRM and (D) relapse. Forest plot showing the HRs of (E) OS and (F) relapse, estimated by univariate regression outcome analysis. CIF, cumulative incidence function; HCT-CI, hematopoietic cell transplantation–specific comorbidity index; MAC, myeloablative conditioning; MMUD, mismatched unrelated donor; MRC, Medical Research Council; MSD, matched sibling donor; NRM, nonrelapse mortality; PIF, primary induction failure.