Figure 2.
Three- or 4-generation pedigrees collected for family 1 and family 2. The first illustrates the segregation of p.R564Q with ET and CLL in family 1. The proband in family 2 was identified to have the p.R564L variant. Her son is reported to have thrombocytosis (∼500 × 103/μL) but has not had genetic testing. +, positive for JAK2 variant; –, negative for JAK2 variant; dx, diagnosed.
