FigureĀ 3.
CBA and molecular evaluation of chromosomal mimicry in MGB-Mimicry-001 findings. Conventional cytogenetic studies (karyotyping and FISH) are shown on the left. Molecular confirmation with OGM is shown on the right. In the top panel, CBA and FISH studies detect a t(9;22)(q34;q11.2) with BCR::ABL1 fusion by FISH. OGM notes rearrangements on chromosomes 9 and 22 that do not overlap with BCR or ABL1. In the bottom panel, CBA, FISH, and OGM is showing a positive control with a confirmed t(9;22), leading to BCR::ABL1.

CBA and molecular evaluation of chromosomal mimicry in MGB-Mimicry-001 findings. Conventional cytogenetic studies (karyotyping and FISH) are shown on the left. Molecular confirmation with OGM is shown on the right. In the top panel, CBA and FISH studies detect a t(9;22)(q34;q11.2) with BCR::ABL1 fusion by FISH. OGM notes rearrangements on chromosomes 9 and 22 that do not overlap with BCR or ABL1. In the bottom panel, CBA, FISH, and OGM is showing a positive control with a confirmed t(9;22), leading to BCR::ABL1.

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